After configuring the appropriate tools for the laptops, smartphones, servers, etc. you need to back up, backup solutions automatically take care of backing up and/or synchronizing your vital data.
Be careful, though: always have a remote backup and a local backup. Neither you nor we at 100% are protected against fire, etc...
For the most demanding members in terms of security requirements, 24PM backup can be carried out on highly redundant infrastructures, making data loss a mathematical probability of almost zero.